Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8912941 | 1.00 | RAB9A (0.34) | RAB9ANPC1MAPTF11MAPK1 | |
| SCHEMBL8912643 | 0.81 | MAPK1 (0.43) | RAB9ANPC1MAPTF11MAPK1 | |
| SCHEMBL8912655 | 0.81 | MAPK1 (0.43) | RAB9ANPC1MAPTF11MAPK1 | |
| SCHEMBL8914900 | 0.68 | F11 (0.39) | RAB9ANPC1MAPTF11LMNA | |
| SCHEMBL8914891 | 0.68 | F11 (0.39) | RAB9ANPC1MAPTF11LMNA | |
| SCHEMBL8916315 | 0.68 | DCAF1 (0.42) | MAPTF11MAPK1LMNASMN1; SMN2 | |
| SCHEMBL8916020 | 0.68 | DCAF1 (0.35) | RAB9ANPC1MAPTF11MAPK1 | |
| SCHEMBL8916027 | 0.68 | DCAF1 (0.35) | RAB9ANPC1MAPTF11MAPK1 | |
| SCHEMBL8916323 | 0.68 | DCAF1 (0.42) | MAPTF11MAPK1LMNASMN1; SMN2 | |
| SCHEMBL27418349 | 0.59 | PTPRA (0.50) | RAB9ANPC1MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7118237-A | — | — | None | — | — | JP | disclosed |
| US-5606073-A | INTERMEDIATES FOR ADENOSINE ANTAGONISTS | EISAI CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| JP-H07118237-A | PROPENOIC ACID DERIVATIVE | EISAI CO LTD | 1995-05-09 | — | — | JP | disclosed |
| EP-0630894-A1 | Propenoic acid derivatives as adenosine A1 antagonists | Eisai Co., Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |