Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.45 |
| ▸ | HTR1B | P28222 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10213320 | 0.86 | GABRA1 (0.47) | HTR1AADRB1HTR1BCYP1A2CYP3A4 | |
| SCHEMBL20599963 | 0.83 | HTR2A (0.63) | HTR1AADRB1HTR1BCYP1A2HTR2C | |
| SCHEMBL707958 | 0.77 | HTR2A (0.70) | HTR1AADRB1HTR1BCYP3A4LMNA | |
| SCHEMBL5692300 | 0.77 | HTR2A (0.70) | HTR1AADRB1HTR1BCYP3A4LMNA | |
| SCHEMBL5950323 | 0.77 | GABRA1 (0.46) | LMNAADRB2KMT2A | |
| SCHEMBL10719680 | 0.77 | GLS (0.48) | HTR1AADRB1HTR1BCYP1A2CYP3A4 | |
| SCHEMBL23792180 | 0.76 | HTR1A (0.55) | HTR1AADRB1HTR1BCYP1A2CYP3A4 | |
| SCHEMBL2633083 | 0.76 | DAO (0.50) | HTR1BCYP1A2CYP3A4KDM4EMAPK1 | |
| SCHEMBL951816 | 0.76 | AHR (0.50) | HTR1AADRB1HTR1BCYP1A2CYP3A4 | |
| SCHEMBL38665028 | 0.76 | DAO (0.50) | HTR1BCYP1A2CYP3A4KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5609649-A | Tinctorial composition for keratinous fibers containing oxidation dye precursors and couplers derived from 4-hydroxyindole, and dyeing method using them | L'OREAL (FR) | 1997-03-11 | — | — | US | disclosed |