SCHEMBL8913287

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9570630	0.87	ALDH1A1 (0.67)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL9570559	0.83	MAPT (0.83)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL22971780	0.83	MAOA (1.00)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL1411677	0.82	MAPT (0.71)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL8182157	0.79	MAPT (0.62)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL22971778	0.79	MAOA (1.00)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL290413	0.78	MAPT (0.75)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL8182679	0.78	PTPN1 (0.79)	ALDH1A1NPSR1MAOACISD1MAOB
	SCHEMBL13846702	0.77	PPARG (0.59)	ALDH1A1NPSR1MAOACISD1MAOB
	Glitazone SCHEMBL623021	0.77	MAPT (0.73)	ALDH1A1NPSR1MAOACISD1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.