⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376048 | 0.91 | — | — | |
| SCHEMBL6558915 | 0.90 | — | — | |
| SCHEMBL8325457 | 0.89 | — | — | |
| SCHEMBL6558909 | 0.89 | — | — | |
| SCHEMBL8872802 | 0.87 | AGTR1 (0.64) | — | |
| SCHEMBL8029160 | 0.83 | GPR4 (0.52) | — | |
| SCHEMBL8384340 | 0.81 | AGTR1 (0.55) | — | |
| SCHEMBL9282165 | 0.81 | — | — | |
| SCHEMBL9282159 | 0.81 | AGTR1 (0.45) | — | |
| SCHEMBL8327383 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6080664-A | — | — | None | — | — | JP | disclosed |
| US-5665881-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ANGIOTENSIN II ANTAGONIST | THE GREEN CROSS CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0569013-B1 | Quinoline compounds as angiotensin II antagonists | GREEN CROSS CORP (JP) | 1996-08-28 | — | — | EP | disclosed |
| EP-0693478-A1 | Quinoline compounds | THE GREEN CROSS CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5478832-A | Angiotensin II antagonists; cardiovascular disorders | THE GREEN CROSS CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| JP-H0680664-A | NEW QUINOLINE DERIVATIVE | ASAHI GLASS CO LTD | 1994-03-22 | — | — | JP | disclosed |
| EP-0569013-A1 | Quinoline compounds as angiotensin II antagonists | THE GREEN CROSS CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |