Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921897 | 0.93 | AVPR2 (0.54) | HTTTDP1AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8717040 | 0.83 | AVPR2 (0.49) | HTTTDP1AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8720267 | 0.81 | AVPR2 (0.58) | HTTTDP1AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8722874 | 0.81 | AVPR2 (0.58) | HTTTDP1AVPR2AVPR1AALDH1A1 | |
| SCHEMBL8901168 | 0.80 | AVPR2 (0.54) | AVPR2AVPR1AALDH1A1KMT2APOLB | |
| SCHEMBL8722757 | 0.80 | DRD2 (0.65) | TDP1AVPR2AVPR1AALDH1A1L3MBTL1 | |
| SCHEMBL8902187 | 0.79 | HTR1A (0.67) | TDP1AVPR2AVPR1AALDH1A1L3MBTL1 | |
| SCHEMBL8901177 | 0.79 | HTR1A (0.67) | TDP1AVPR2AVPR1AALDH1A1L3MBTL1 | |
| SCHEMBL8724506 | 0.79 | HTR1A (0.67) | TDP1AVPR2AVPR1AALDH1A1L3MBTL1 | |
| SCHEMBL8907755 | 0.79 | AVPR2 (0.53) | HTTTDP1AVPR2AVPR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014689-A1 | ARYL-PIPERAZINE CYCLIC AMINE DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | PIERRE FABRE MEDICAMENT (FR) | 1997-04-24 | — | — | WO | disclosed |