Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | PYGL | P06737 | 6/20 | 0.36 |
| ▸ | PYGM | P11217 | 6/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952272 | 0.81 | KDM4E (0.41) | TP53PYGLPYGMMAPTNR3C2 | |
| SCHEMBL9238272 | 0.80 | TP53 (0.44) | TP53PYGLPYGMALDH1A1 | |
| SCHEMBL8913434 | 0.80 | TP53 (0.53) | TP53MAPTNR3C2 | |
| SCHEMBL6945824 | 0.76 | NR3C2 (0.44) | PYGLPYGMMAPTNR3C2ALDH1A1 | |
| SCHEMBL9236272 | 0.76 | KMT2A (0.39) | TP53NR3C2ALDH1A1LMNA | |
| SCHEMBL6953545 | 0.72 | PYGM (0.49) | PYGLPYGMNR3C2 | |
| SCHEMBL6942375 | 0.72 | MAPT (0.52) | TP53PYGLPYGMMAPTTSHR | |
| SCHEMBL6952275 | 0.71 | NR3C2 (0.42) | TP53PYGLPYGMNR3C2ALDH1A1 | |
| SCHEMBL6952771 | 0.71 | NR3C2 (0.42) | PYGLPYGMMAPTNR3C2LMNA | |
| SCHEMBL6950023 | 0.69 | LMNA (0.46) | PYGLPYGMCYP3A4TSHRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657434-A1 | Arylsubstituted -alkoxy-1,4-dihydropyridin-5-carbonic acid esters with cerebral activity | BAYER AG (DE) | 1995-06-14 | — | — | EP | disclosed |