Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.38 |
| ▸ | RHOC | P08134 | 1/20 | 0.37 |
| ▸ | RHOA | P61586 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.37 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8911024 | 0.87 | CES2 (0.46) | CES2TACR1GAAPTPN1P2RX1 | |
| SCHEMBL8912040 | 0.85 | CES2 (0.47) | CES2TACR1GAAPTPN1P2RX1 | |
| SCHEMBL23091848 | 0.82 | CES2 (0.55) | CES2TACR1GAAPTPN1P2RX1 | |
| SCHEMBL29115453 | 0.82 | CES2 (0.55) | CES2TACR1GAAPTPN1P2RX1 | |
| SCHEMBL23091832 | 0.82 | CES2 (0.64) | CES2TACR1GAAPTPN1P2RX1 | |
| SCHEMBL8912732 | 0.81 | CES2 (0.43) | CES2TACR1GAAPTPN1P2RX1 | |
| SCHEMBL8911789 | 0.81 | PLOD2 (0.46) | CES2PTPN1PLOD2LMNAMAPT | |
| SCHEMBL8912055 | 0.80 | RAB9A (0.39) | GAAPLOD2PLOD3PLOD1MEN1 | |
| SCHEMBL8913481 | 0.80 | PLOD2 (0.38) | HDAC3HDAC8HDAC6PLOD2NOTUM | |
| SCHEMBL29115374 | 0.79 | CES2 (0.52) | CES2TACR1GAAPTPN1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |