Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RHOC | P08134 | 5/20 | 0.39 |
| ▸ | RHOA | P61586 | 5/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8913540 | 0.87 | CES2 (0.48) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL8912040 | 0.86 | CES2 (0.47) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL8911566 | 0.83 | RAB9A (0.38) | GAAPLOD2CYP3A4PLOD3PLOD1 | |
| SCHEMBL23091848 | 0.80 | CES2 (0.55) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL29115453 | 0.80 | CES2 (0.55) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL23091832 | 0.79 | CES2 (0.64) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL29115374 | 0.77 | CES2 (0.52) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL8911336 | 0.77 | CES2 (0.52) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL8912732 | 0.76 | CES2 (0.43) | CES2TACR1GAARHOCRHOA | |
| SCHEMBL4944429 | 0.74 | CES2 (0.57) | CES2TACR1GAARHOCRHOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618547-A | ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-04-08 | — | — | US | disclosed |
| US-4870109-A | ANIMAL HUSBANDRY | ELI LILLY AND COMPANY (US) | 1989-09-26 | — | — | US | disclosed |