Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8806406 | 0.86 | HDAC4 (0.46) | PPARGPPARDPPARATNFKDM4E | |
| SCHEMBL7439510 | 0.80 | BCHE (0.49) | PPARDPPARAALDH1A1KMT2ANPSR1 | |
| SCHEMBL12923997 | 0.77 | PDCD1 (0.47) | PPARGPPARDPPARAGAAPDE4A | |
| SCHEMBL7434909 | 0.75 | ACHE (0.44) | TNFGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL6406971 | 0.74 | PDE4A (0.46) | PPARGPPARDPPARAALDH1A1PDE4A | |
| SCHEMBL84033 | 0.73 | PPARG (0.53) | PPARGPPARDPPARAALDH1A1CYP1A2 | |
| SCHEMBL7434608 | 0.72 | L3MBTL1 (0.41) | PPARGSMN1; SMN2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL7439241 | 0.72 | HDAC4 (0.46) | TNFSMN1; SMN2ALDH1A1KMT2ANPSR1 | |
| SCHEMBL7442073 | 0.71 | TBK1 (0.38) | GAASMN1; SMN2ALDH1A1L3MBTL1ACHE | |
| SCHEMBL16231311 | 0.70 | PPARG (0.57) | PPARGPPARDPPARATNFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703071-A | Tropolone derivatives and pharmaceutical composition thereof for preventing and treating ischemic diseases | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |