Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123347 | 0.84 | SIRT2 (0.55) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL39113 | 0.82 | SIRT2 (0.61) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29773981 | 0.82 | SIRT2 (0.61) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL277619 | 0.82 | HDAC3 (0.54) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15459767 | 0.81 | SIRT2 (0.51) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL125531 | 0.81 | SIRT2 (0.51) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5000788 | 0.80 | NPC1 (0.52) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12254053 | 0.80 | HDAC3 (0.52) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8923522 | 0.79 | SIRT2 (0.55) | SIRT2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10299923 | 0.78 | HDAC3 (0.54) | SIRT2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112143140-A | Cold-resistant PVC sheet and preparation process thereof | 温州一派塑业有限公司 | 2020-12-29 | — | — | CN | claimed |
| US-7235698-B2 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-06-26 | — | — | US | claimed |
| US-20060084820-A1 | Enantioselective, catalytic allylation of ketones and olefins | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-20 | — | — | US | claimed |
| CN-112143140-A | Cold-resistant PVC sheet and preparation process thereof | 温州一派塑业有限公司 | 2020-12-29 | — | — | CN | disclosed |
| US-20190209572-A1 | BIFUNCTIONAL ANTIFUNGAL AGENTS AND METHODS OF TREATING FUNGAL INFECTION | MERCK SHARP & DOHME CORP. | 2019-07-11 | — | — | US | disclosed |
| WO-2018035424-A1 | BIFUNCTIONAL ANTIFUNGAL AGENTS AND METHODS OF TREATING FUNGAL INFECTION | YALE UNIVERSITY (US) | 2018-02-22 | — | — | WO | disclosed |
| US-20120082645-A1 | 2'-C-METHYL-RIBOFURANOSYL CYTIDINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | XENOPORT, INC. (US) | 2012-04-05 | — | — | US | disclosed |
| US-8058260-B2 | 2′-C-methyl-ribofuranosyl cytidine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-7803785-B2 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-20100016254-A1 | GEMCITABINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-7608602-B2 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2009-10-27 | — | — | US | disclosed |
| WO-2001020331-A1 | SUBSTRATES AND SCREENING METHODS FOR TRANSPORT PROTEINS | XENOPORT, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| WO-1999064049-A9 | NOVEL ANTIBACTERIAL AGENTS | ADVANCED MEDICINE INC (US) | 2001-01-18 | — | — | WO | disclosed |
| WO-2000069892-A1 | GLYCOPEPTIDE ANTIBIOTICS, COMBINATORIAL LIBRARIES OF GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF PRODUCING SAME | PRINCETON UNIVERSITY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000066528-A2 | QUINONES FOR TREATMENT OF DISEASES | SLIL BIOMEDICAL CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |
| EP-1005356-A1 | NOVEL ANTIBACTERIAL AGENTS | Advanced Medicine, Inc. (US) | 2000-06-07 | — | — | EP | disclosed |
| WO-2000004044-A1 | GLYCOPEPTIDE ANTIBIOTICS, COMBINATORIAL LIBRARIES OF GLYCOPEPTIDE ANTIBIOTICS AND METHODS OF PRODUCING SAME | PRINCETON UNIVERSITY (US) | 2000-01-27 | — | — | WO | disclosed |
| WO-1999064049-A1 | NOVEL ANTIBACTERIAL AGENTS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| US-5026838-A | Starting materials for polynucleotides | NIPPON ZEON CO., LTD. (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0216357-A2 | Phosphoramidite compounds and process for production thereof | NIPPON ZEON CO., LTD. (JP) | 1987-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084820-A1 | Enantioselective, catalytic allylation of ketones and olefins | AKR1C2, TECR, AKR1C4 | SIRT2 2024/4885HDAC3 1120/4885HDAC4 1240/4885 |
| US-20120082645-A1 | 2'-C-METHYL-RIBOFURANOSYL CYTIDINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MTAP, NSUN2, CDA | SIRT2 958/4885HDAC3 1697/4885HDAC4 3581/4885 |
| US-20190209572-A1 | BIFUNCTIONAL ANTIFUNGAL AGENTS AND METHODS OF TREATING FUNGAL INFECTION | ERG28, PAICS, BAK1 | SIRT2 838/4885HDAC3 341/4885HDAC4 209/4885 |
| US-20100016254-A1 | GEMCITABINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | TYMP, GDA, GCG | SIRT2 1874/4885HDAC3 2080/4885HDAC4 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.