SCHEMBL8914799

SCHEMBL8914799

CO[Si](c1cccs1)(c1cccs1)c1cccs1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RPS6KB2 Q9UBS0 2/20 0.35
DAO P14920 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
FBP1 P09467 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
CYP1A1 P04798 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP1B1 Q16678 2/20 0.32
DPP4 P27487 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
PDGFRB P09619 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16613151 0.81 RPS6KB2 (0.35) RPS6KB2KDM4EMEN1MAPTKMT2A
SCHEMBL14958040 0.81 RPS6KB2 (0.35) RPS6KB2KDM4EMEN1MAPTKMT2A
SCHEMBL27473536 0.79 RPS6KB2 (0.34) RPS6KB2KDM4EMEN1MAPTKMT2A
SCHEMBL19875003 0.79 RPS6KB2 (0.32) RPS6KB2ALDH1A1HPGDNPC1RAB9A
SCHEMBL19875057 0.74 RPS6KB2 (0.32) RPS6KB2ALDH1A1HPGDNPC1RAB9A
SCHEMBL19874953 0.73 CYP1A2 (0.31) RPS6KB2MEN1KMT2ACYP1A2
SCHEMBL20550992 0.72 FBP1 (0.36) DAOKDM4EMEN1MAPTKMT2A
SCHEMBL2341397 0.72
SCHEMBL2290788 0.72 FBP1 (0.36) DAOKDM4EMEN1MAPTKMT2A
SCHEMBL4351074 0.71 TDO2 (0.33) RPS6KB2KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9241265-A None JP disclosed
JP-H09241265-A TETRATHIENYLSILANE DERIVATIVE AND ITS PRODUCTION NAKAYAMA JUZO 1997-09-16 JP disclosed