Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8914980 | 0.71 | GPR35 (0.35) | GPR35 | |
| SCHEMBL8914654 | 0.71 | ALDH1A1 (0.34) | ALDH1A1GPR84SMN1; SMN2CXCR2 | |
| SCHEMBL8916181 | 0.71 | ALDH1A1 (0.40) | ALDH1A1GPR35SMN1; SMN2 | |
| SCHEMBL8915133 | 0.70 | ALDH1A1 (0.33) | ALDH1A1GPR84SMN1; SMN2 | |
| SCHEMBL12060960 | 0.66 | GPR35 (0.46) | GPR35 | |
| SCHEMBL18876139 | 0.65 | GPR35 (0.36) | GPR35 | |
| SCHEMBL12060959 | 0.65 | GPR35 (0.42) | GPR35 | |
| SCHEMBL1654430 | 0.64 | ALDH1A1 (0.44) | ALDH1A1GPR84SMN1; SMN2THRB | |
| SCHEMBL11718129 | 0.64 | ALDH1A1 (0.38) | ALDH1A1GPR84SMN1; SMN2 | |
| SCHEMBL11719908 | 0.64 | ALDH1A1 (0.38) | ALDH1A1GPR84SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684165-A | FOR USE IN NONLINEAR OPTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5432286-A | Nonlinear optics | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| EP-0592919-A1 | Substituted thieno[3,2-b]thiophenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-20 | — | — | EP | disclosed |