Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917200 | 0.75 | GAA (0.47) | ALDH1A1HPGDHSD17B10TSHRMAPT | |
| SCHEMBL8914654 | 0.71 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8914820 | 0.71 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2GPR35 | |
| SCHEMBL8915133 | 0.70 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9031570 | 0.66 | GPR84 (0.45) | TSHRSMN1; SMN2 | |
| SCHEMBL9031572 | 0.66 | XDH (0.44) | TSHRSMN1; SMN2 | |
| SCHEMBL1653820 | 0.64 | LMNA (0.37) | HSD17B10MAPTNPSR1LMNARAB9A | |
| SCHEMBL22438891 | 0.63 | THRA (0.58) | ALDH1A1MAPTKMT2ARAB9ANPC1 | |
| SCHEMBL14261948 | 0.63 | ESR1 (0.41) | NPSR1L3MBTL1KDM4ELMNAPTGS2 | |
| SCHEMBL14261939 | 0.62 | MAPK1 (0.42) | HSD17B10TSHRMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684165-A | FOR USE IN NONLINEAR OPTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |
| US-5432286-A | Nonlinear optics | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-11 | — | — | US | disclosed |
| EP-0592919-A1 | Substituted thieno[3,2-b]thiophenes and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-20 | — | — | EP | disclosed |