Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | EDNRB | P24530 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511671 | 0.92 | HDAC6 (0.39) | PTGDR2EDNRBMEN1KMT2A | |
| SCHEMBL8915668 | 0.84 | HDAC6 (0.37) | PTGDR2MEN1KMT2A | |
| SCHEMBL7506489 | 0.81 | PTGDR2 (0.35) | PTGDR2MEN1KMT2A | |
| SCHEMBL7571920 | 0.77 | HDAC6 (0.41) | PTGDR2EDNRBMEN1KMT2A | |
| SCHEMBL7516884 | 0.76 | FEN1 (0.37) | EDNRBMEN1KMT2A | |
| SCHEMBL7512664 | 0.71 | SLC10A2 (0.43) | EDNRB | |
| SCHEMBL7574883 | 0.70 | PTGDR2 (0.40) | PTGDR2EDNRBMEN1KMT2A | |
| SCHEMBL7512320 | 0.63 | NMT2 (0.32) | MEN1KMT2A | |
| SCHEMBL4310387 | 0.63 | — | — | |
| SCHEMBL30765992 | 0.60 | MAPT (0.52) | MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654309-A | KIDNEY, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-05 | — | — | US | claimed |