Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 15/20 | 0.73 |
| ▸ | MMP2 | P08253 | 14/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.60 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5191094 | 0.88 | MMP9 (0.89) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL6720186 | 0.88 | MMP9 (0.89) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL7301154 | 0.85 | MMP9 (1.00) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL8579007 | 0.83 | MMP9 (0.72) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL8912407 | 0.81 | MMP2 (0.67) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL7468990 | 0.81 | MMP9 (0.83) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL7468980 | 0.81 | MMP9 (0.83) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL13799679 | 0.81 | MMP9 (0.83) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL22500298 | 0.81 | MMP9 (0.83) | MMP9MMP2MEN1POLBKMT2A | |
| SCHEMBL8603495 | 0.81 | MMP9 (0.83) | MMP9MMP2MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663174-A | ANTIINFLAMMATORY AGENTS, INHIBITOR OF KINASES, ANTIARTHRITIC AGENTS | PHARNO-WEDROPHARM GMBH (DE) | 1997-09-02 | — | — | US | disclosed |
| EP-0602028-B1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO WEDROPHARM GMBH (DE) | 1996-01-17 | — | — | EP | disclosed |
| WO-1993005014-A1 | AROMATIC SULFONAMIDE DERIVATIVES, THEIR USE AS ENZYME INHIBITORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PHARNO-WEDROPHARM GMBH (DE) | 1993-03-18 | — | — | WO | disclosed |