Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | PPARD | Q03181 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785667 | 0.88 | PTGS1 (0.62) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL6861607 | 0.87 | PTGS1 (0.76) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL30464902 | 0.87 | PTGS1 (0.76) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL16131104 | 0.86 | PTGS1 (0.74) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL2231075 | 0.86 | PTGS1 (0.66) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL2227914 | 0.86 | PTGS1 (0.66) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL6860845 | 0.86 | PTGS1 (0.66) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL8743388 | 0.85 | PTGS1 (0.72) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL14299273 | 0.85 | PTGS1 (0.72) | PTGS1MEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL6860847 | 0.85 | PTGS1 (0.72) | PTGS1MEN1KMT2ACYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | claimed |
| EP-3280411-B1 | REDUCTION IN CPC TASTE AVERSION BY REDUCING CPC ACTIVATION OF TRPA1 RECEPTORS, TPRV1 RECEPTORS, OR BOTH | PROCTER & GAMBLE (US) | 2020-02-19 | — | — | EP | claimed |
| EP-3503733-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | Iowa State University Research Foundation, Inc. (US) | 2019-07-03 | — | — | EP | claimed |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-02-14 | — | — | US | claimed |
| US-9993410-B2 | Reduction in CPC taste aversion by reducing CPC activation of TRPA1, TPRV1, or both | THE PROCTER & GAMBLE COMPANY (US) | 2018-06-12 | — | — | US | claimed |
| WO-2018039376-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-03-01 | — | — | WO | claimed |
| EP-3280411-A1 | REDUCTION IN CPC TASTE AVERSION BY REDUCING CPC ACTIVATION OF TRPA1 RECEPTORS, TPRV1 RECEPTORS, OR BOTH | The Procter and Gamble Company (US) | 2018-02-14 | — | — | EP | claimed |
| US-20170333325-A1 | REDUCTION IN CPC TASTE AVERSION BY REDUCING CPC ACTIVATION OF TRPA1, TPRV1, OR BOTH | PROCTER & GAMBLE (US) | 2017-11-23 | — | — | US | claimed |
| WO-2016164676-A1 | REDUCTION IN CPC TASTE AVERSION BY REDUCING CPC ACTIVATION OF TRPA1 RECEPTORS, TPRV1 RECEPTORS, OR BOTH | THE PROCTER & GAMBLE COMPANY (US) | 2016-10-13 | — | — | WO | claimed |
| US-20160296445-A1 | REDUCTION IN CPC TASTE AVERSION BY REDUCING CPC ACTIVATION OF TRPA1, TPRV1, OR BOTH | THE PROCTER & GAMBLE COMPANY | 2016-10-13 | — | — | US | claimed |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4382518-A2 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | Iowa State University Research Foundation, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | FIRMENICH INCORPORATED (US) | 2024-04-04 | — | — | US | disclosed |
| EP-3503733-B1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-3416729-B1 | PRO-FRAGRANCE COMPOSITION | AQDOT LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-20100248390-A1 | COMPOSITIONS AND METHODS FOR IDENTIFYING LIGANDS OF ODORANT RECEPTORS | DUKE UNIVERSITY (US) | 2010-09-30 | — | — | US | disclosed |
| WO-1999021006-A9 | PHARMACEUTICAL GRADE VALERIAN, BLACK COHOSH, VITEX AGNUS-CASTUS, BILBERRY AND MILK THISTLE | PHARMAPRINT INC (US) | 1999-07-08 | — | — | WO | disclosed |
| WO-1999021006-A1 | PHARMACEUTICAL GRADE VALERIAN, BLACK COHOSH, VITEX AGNUS-CASTUS, BILBERRY AND MILK THISTLE | PHARMAPRINT, INC. (US) | 1999-04-29 | — | — | WO | disclosed |
| EP-0900375-A1 | PHARMACEUTICAL GRADE BOTANICAL DRUGS | Pharmaprint, Inc. (US) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997039355-A1 | PHARMACEUTICAL GRADE BOTANICAL DRUGS | PHARMAPRINT, INC. (US) | 1997-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108040-A1 | HIGH INTENSITY SWEETENERS | TAS2R40, TAS2R60, TAS1R1 | PTGS1 1786/4885MEN1 2644/4885KMT2A 2697/4885 |
| US-20160296445-A1 | REDUCTION IN CPC TASTE AVERSION BY REDUCING CPC ACTIVATION OF TRPA1, TPRV1, OR BOTH | TRPA1, TRPV1, TRPV4 | PTGS1 3528/4885MEN1 3557/4885KMT2A 4366/4885 |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | PTGS1 632/4885MEN1 1913/4885KMT2A 1269/4885 |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | PTGS1 632/4885MEN1 1913/4885KMT2A 1269/4885 |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | PTGS1 632/4885MEN1 1913/4885KMT2A 1269/4885 |
| US-20170333325-A1 | REDUCTION IN CPC TASTE AVERSION BY REDUCING CPC ACTIVATION OF TRPA1, TPRV1, OR BOTH | TRPA1, TRPV1, TRPV4 | PTGS1 3528/4885MEN1 3557/4885KMT2A 4366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.