Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10427642 | 0.79 | ERBB2 (0.53) | ERBB2MAPTKDM4ECYP3A4ADORA2A | |
| SCHEMBL460510 | 0.77 | ALOX15 (0.50) | ALOX15SLC22A12HTR2BHTR5ATDO2 | |
| SCHEMBL27664892 | 0.77 | ALOX15 (0.50) | ALOX15SLC22A12HTR2BHTR5ATDO2 | |
| SCHEMBL30021764 | 0.74 | ALOX15 (0.48) | ALOX15SLC22A12HTR2BHTR5ATDO2 | |
| Hydrochloric Acid SCHEMBL4703144 | 0.74 | ALOX15 (0.48) | ALOX15SLC22A12HTR2BHTR5ATDO2 | |
| SCHEMBL3920052 | 0.73 | CYP2A6 (0.40) | PTGS1PTGS2CHEK1GSK3B | |
| SCHEMBL8914679 | 0.73 | PTGS1 (0.39) | ALOX15HTR2BHTR5ATDO2MAPT | |
| SCHEMBL14525863 | 0.72 | ALDH1A1 (0.50) | ALOX15SLC22A12HTR2BHTR5ATDO2 | |
| SCHEMBL14525924 | 0.72 | ALDH1A1 (0.50) | ALOX15SLC22A12HTR2BHTR5ATDO2 | |
| Pyridine SCHEMBL28393899 | 0.69 | NOTUM (0.52) | ALOX15SLC22A12HTR2BHTR5ATDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639753-A | CONTROLLING INSECTS IN AGRICULTURE CROPS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5532367-A | LARVICIDES | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5521190-A | USEFUL AGAINST TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1994027439-A1 | INSECTICIDAL PTERIDINES AND 8-DEAZAPTERIDINES | FMC CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |