Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RORB | Q92753 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003 | 0.85 | TDP1 (0.39) | HTTALOX15KDM4ETDP1CYP2A6 | |
| SCHEMBL23581979 | 0.80 | RORB (0.54) | TDO2RORBADORA2AADORA1 | |
| SCHEMBL29865338 | 0.80 | RORB (0.54) | TDO2RORBADORA2AADORA1 | |
| SCHEMBL1146096 | 0.80 | HDAC1 (0.51) | HDAC1ALDH1A1HTTKDM4ETDP1 | |
| SCHEMBL29768457 | 0.80 | HDAC1 (0.51) | HDAC1ALDH1A1HTTKDM4ETDP1 | |
| SCHEMBL9715965 | 0.78 | KDM4E (0.48) | ALDH1A1HTTHSD17B10ALOX15KDM4E | |
| SCHEMBL5826057 | 0.78 | HDAC1 (0.50) | HDAC1ALDH1A1HTTKDM4ETDP1 | |
| SCHEMBL29428995 | 0.74 | ALDH1A1 (0.40) | HDAC1ALDH1A1HSD17B10TDP1ADORA2A | |
| SCHEMBL8915138 | 0.73 | ALOX15 (0.37) | PTGS1PTGS2TDO2ALOX15KDM4E | |
| SCHEMBL2975854 | 0.72 | CNR2 (0.46) | PTGS1PTGS2ALDH1A1HTTRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639753-A | CONTROLLING INSECTS IN AGRICULTURE CROPS | FMC CORPORATION (US) | 1997-06-17 | — | — | US | disclosed |
| US-5532367-A | LARVICIDES | FMC CORPORATION (US) | 1996-07-02 | — | — | US | disclosed |
| US-5521190-A | USEFUL AGAINST TOBACCO BUDWORM | FMC CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |
| WO-1994027439-A1 | INSECTICIDAL PTERIDINES AND 8-DEAZAPTERIDINES | FMC CORPORATION (US) | 1994-12-08 | — | — | WO | disclosed |