SCHEMBL8915214

SCHEMBL8915214

Cc1nc2ccccc2cc1-c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.50
NPC1 O15118 5/20 0.50
ALDH1A1 P00352 5/20 0.49
HPGD P15428 4/20 0.49
STAT3 P40763 2/20 0.49
GAA P10253 1/20 0.49
CCR1 P32246 3/20 0.43
CCR5 P51681 3/20 0.43
CCR8 P51685 3/20 0.43
METAP1 P53582 3/20 0.43
CYP1A2 P05177 3/20 0.43
LMNA P02545 2/20 0.43
POLB P06746 1/20 0.43
BLM P54132 1/20 0.43
HIF1A Q16665 1/20 0.43
DOHH Q9BU89 1/20 0.43
P4HTM Q9NXG6 1/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
HTT P42858 2/20 0.43
PSMB5 P28074 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22238047 0.83 METAP2 (0.49) KDM4ENPC1ALDH1A1HPGDMETAP1
SCHEMBL28765720 0.81 KDM4E (0.56) KDM4ENPC1ALDH1A1HPGDCCR1
SCHEMBL3706710 0.80 OPRK1 (0.47) KDM4ENPC1ALDH1A1HPGDSTAT3
SCHEMBL28962070 0.79 NPC1 (0.53) KDM4ENPC1ALDH1A1HPGDGAA
SCHEMBL30161832 0.79 BTK (0.51) KDM4ENPC1ALDH1A1HPGDGAA
SCHEMBL29982775 0.79 BTK (0.51) KDM4ENPC1ALDH1A1HPGDGAA
SCHEMBL20081269 0.79 METAP1 (0.46) KDM4ENPC1CCR1CCR5CCR8
SCHEMBL7207055 0.78 KDM4E (0.44) KDM4ENPC1ALDH1A1HPGDCCR1
SCHEMBL4725361 0.77 KDM4E (0.55) KDM4ENPC1ALDH1A1HPGDGAA
Acridine SCHEMBL28454794 0.76 ALDH1A1 (0.62) KDM4ENPC1ALDH1A1HPGDCCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5685632-A HEAD ASSEMBLY FOR A BATTER-POWERED LIGHT SOURCE RAYOVAC CORPORATION (US) 1997-11-11 US claimed
US-5685632-A HEAD ASSEMBLY FOR A BATTER-POWERED LIGHT SOURCE RAYOVAC CORPORATION (US) 1997-11-11 US disclosed