Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | QPCT | Q16769 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCL6 | P41182 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915063 | 0.99 | CA9 (0.58) | CA9KMT2AQPCTLMNAGAA | |
| SCHEMBL7966915 | 0.86 | CA9 (0.54) | CA9KMT2AQPCTLMNAHRH2 | |
| SCHEMBL7904143 | 0.83 | KMT2A (0.71) | CA9KMT2ALMNAGAAHRH2 | |
| SCHEMBL7901763 | 0.83 | KMT2A (0.71) | CA9KMT2ALMNAGAAHRH2 | |
| SCHEMBL7104425 | 0.82 | HDAC4 (0.63) | ALDH1A1L3MBTL1 | |
| SCHEMBL8915664 | 0.82 | L3MBTL1 (0.58) | CA9KMT2AQPCTLMNAGAA | |
| SCHEMBL8916496 | 0.81 | L3MBTL1 (0.56) | CA9KMT2AQPCTLMNAGAA | |
| SCHEMBL8917236 | 0.81 | L3MBTL1 (0.56) | CA9KMT2AQPCTLMNAGAA | |
| SCHEMBL8918824 | 0.81 | LMNA (0.55) | CA9KMT2AQPCTLMNAGAA | |
| SCHEMBL8916068 | 0.81 | L3MBTL1 (0.56) | CA9KMT2AQPCTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5696140-A | FOR TREATMENT OF ASTHMA, ALLERGIES, NERVOUS SYSTEM DISORDERS OR CANCER | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1997-12-09 | — | — | US | disclosed |