Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | BCL6 | P41182 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LSS | P48449 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904143 | 1.00 | KMT2A (0.71) | KMT2AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6959672 | 0.88 | RAB9A (0.79) | KMT2AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7966915 | 0.87 | CA9 (0.54) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8915063 | 0.84 | CA9 (0.58) | KMT2AMAPTLMNAALDH1A1RAB9A | |
| SCHEMBL8915308 | 0.83 | CA9 (0.60) | KMT2ALMNAALDH1A1RAB9ANPC1 | |
| SCHEMBL19420177 | 0.82 | RAB9A (0.79) | KMT2AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL6816412 | 0.82 | KMT2A (0.73) | KMT2AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8916892 | 0.81 | L3MBTL1 (0.56) | KMT2AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8916068 | 0.81 | L3MBTL1 (0.56) | KMT2AMAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8916496 | 0.81 | L3MBTL1 (0.56) | KMT2AMAPTLMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197797-B1 | ANTICANCER AGENTS; SKIN DISORDERS | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 2001-03-06 | — | — | US | disclosed |