Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PARL | Q9H300 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1783722 | 0.83 | KMT2A (0.50) | L3MBTL1POLBSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL10512456 | 0.81 | L3MBTL1 (0.50) | L3MBTL1POLBSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL3747944 | 0.78 | L3MBTL1 (0.57) | L3MBTL1PARLPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL7414768 | 0.77 | PKM (0.50) | L3MBTL1POLBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1493760 | 0.76 | PARL (0.56) | L3MBTL1PARLPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL16394281 | 0.74 | POLB (0.56) | HTR7POLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7412162 | 0.73 | POLB (0.40) | POLBSMN1; SMN2ALDH1A1ATMTSHR | |
| SCHEMBL7412166 | 0.72 | KMT2A (0.51) | POLBALDH1A1TSHRHTTHPGD | |
| SCHEMBL10974578 | 0.72 | PARL (0.57) | L3MBTL1PARLSMN1; SMN2ALDH1A1ATM | |
| SCHEMBL6115076 | 0.72 | PARL (0.50) | L3MBTL1PARLPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812827-A1 | Piperidine derivative as intermediates for the preparation of paroxetine and process for their preparation | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1997-12-17 | — | — | EP | disclosed |