Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13604236 | 0.81 | KMT2A (0.71) | POLBSMN1; SMN2HTR7MEN1KMT2A | |
| SCHEMBL5280569 | 0.81 | HTR6 (0.50) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL14476103 | 0.79 | MEN1 (0.73) | POLBSMN1; SMN2HTR7MEN1KMT2A | |
| SCHEMBL9389577 | 0.74 | TSHR (0.59) | POLBMEN1KMT2ALTA4HTSHR | |
| SCHEMBL8915376 | 0.74 | L3MBTL1 (0.50) | POLBSMN1; SMN2HTR7KMT2AALDH1A1 | |
| SCHEMBL10409579 | 0.74 | SIGMAR1 (0.55) | POLBSMN1; SMN2HTR7MEN1KMT2A | |
| SCHEMBL10409520 | 0.74 | SIGMAR1 (0.55) | POLBSMN1; SMN2HTR7MEN1KMT2A | |
| SCHEMBL4957448 | 0.73 | ATM (0.54) | POLBSMN1; SMN2HTR7ALDH1A1LMNA | |
| SCHEMBL12425968 | 0.72 | SMN1; SMN2 (1.00) | POLBSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL13604224 | 0.72 | RCE1 (0.63) | POLBSMN1; SMN2ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150025057-A1 | Triazine-oxadiazoles | NOVARTIS AG (CH) | 2015-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025057-A1 | Triazine-oxadiazoles | OPRK1, OPRD1, OPRL1 | POLB 3927/4885SMN1; SMN2 1684/4885HTR7 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.