Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767147 | 0.96 | MGLL (0.39) | SCN9APPARGMGLLSMPD1PTPN1 | |
| SCHEMBL8766955 | 0.96 | MGLL (0.39) | SCN9APPARGMGLLSMPD1PTPN1 | |
| SCHEMBL8090622 | 0.90 | SMN1; SMN2 (0.39) | GABRA5SCN9ACCR4PPARGSCN5A | |
| SCHEMBL9233299 | 0.87 | GABRA5 (0.37) | GABRA5SCN9APPARGSCN5ASMPD1 | |
| SCHEMBL8099518 | 0.86 | PPARG (0.40) | SCN9APPARGSCN5AMGLLSMPD1 | |
| SCHEMBL8105616 | 0.86 | PPARG (0.40) | SCN9APPARGSCN5AMGLLSMPD1 | |
| SCHEMBL8915506 | 0.86 | EGLN1 (0.43) | GABRA5SMPD1 | |
| SCHEMBL8098997 | 0.85 | PPARG (0.45) | PPARGMGLLSMPD1 | |
| SCHEMBL8099012 | 0.84 | SMPD1 (0.42) | GABRA5SCN9APPARGSMPD1PTPN1 | |
| SCHEMBL8103943 | 0.84 | SMPD1 (0.42) | GABRA5SCN9APPARGSMPD1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673931-B1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AG (DE) | 1997-08-13 | — | — | EP | disclosed |
| EP-0673931-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |