Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916199 | 0.80 | KMT2A (0.39) | SMN1; SMN2 | |
| SCHEMBL7700928 | 0.76 | DRD2 (0.55) | DRD2SLC6A4CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL8917845 | 0.75 | KCNA3 (0.36) | DRD2SLC6A4HTR2CCHRNB2CHRNA4 | |
| SCHEMBL8917953 | 0.73 | PSMB8 (0.40) | DRD2SLC6A4 | |
| SCHEMBL5584733 | 0.73 | HTR2C (0.62) | SLC6A4HTR2C | |
| SCHEMBL3208274 | 0.72 | HTR2C (0.60) | SLC6A4HTR2C | |
| SCHEMBL8991823 | 0.71 | DRD2 (0.35) | DRD2SLC6A4HTR2C | |
| SCHEMBL8917923 | 0.71 | MAPT (0.39) | DRD2SLC6A4SMN1; SMN2 | |
| SCHEMBL8920622 | 0.71 | ALDH1A1 (0.39) | DRD2SLC6A4SMN1; SMN2 | |
| SCHEMBL8918038 | 0.71 | ADORA2A (0.37) | ADORA2ACHRNB2CHRNA4SMN1; SMN2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |