Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920622 | 0.88 | ALDH1A1 (0.39) | MAPTSMN1; SMN2ALDH1A1DRD2SLC6A4 | |
| SCHEMBL8917899 | 0.82 | CYP11B1 (0.40) | DRD2SLC6A4STSHTR2ADRD3 | |
| SCHEMBL20809217 | 0.82 | HTR2C (0.46) | MAPTALOX15SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL8917953 | 0.81 | PSMB8 (0.40) | ALOX15ALDH1A1DRD2SLC6A4PSMB8 | |
| Hydrochloric Acid SCHEMBL20135194 | 0.81 | HTR2C (0.47) | MAPTALOX15SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL7700928 | 0.78 | DRD2 (0.55) | SMN1; SMN2ALDH1A1DRD2SLC6A4HTR2A | |
| SCHEMBL8920208 | 0.77 | PTPN1 (0.43) | ALDH1A1DRD2SLC6A4TSHRPSMB8 | |
| SCHEMBL8916199 | 0.76 | KMT2A (0.39) | MAPTSMN1; SMN2ALDH1A1POLBTSHR | |
| SCHEMBL8916173 | 0.73 | PTPN1 (0.40) | MAPTSMN1; SMN2ALDH1A1DRD2SLC6A4 | |
| SCHEMBL8918420 | 0.73 | PTPN1 (0.40) | DRD2SLC6A4KDM4EHTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |