Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 9/20 | 0.33 |
| ▸ | TP53 | P04637 | 7/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920541 | 0.82 | ADRB1 (0.34) | MAPTTP53LMNAALDH1A1KDM4E | |
| SCHEMBL8915792 | 0.70 | MAPT (0.58) | MAPTTP53LMNAUSP2THRB | |
| SCHEMBL8917207 | 0.70 | ALDH1A1 (0.35) | SMN1; SMN2TSHRALDH1A1KDM4EPOLB | |
| SCHEMBL1367739 | 0.69 | ADRB1 (0.42) | SMN1; SMN2TSHRALDH1A1KDM4EPOLB | |
| SCHEMBL30938252 | 0.68 | SMN1; SMN2 (0.35) | SMN1; SMN2RAB9AL3MBTL1TSHRNPC1 | |
| SCHEMBL6329505 | 0.65 | CA2 (0.38) | SMN1; SMN2RAB9ATSHRNPC1MAPT | |
| SCHEMBL2094381 | 0.64 | SMN1; SMN2 (0.32) | SMN1; SMN2RAB9ANPC1MAPTLMNA | |
| SCHEMBL28388316 | 0.64 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9ATSHRNPC1CASP3 | |
| SCHEMBL2091686 | 0.64 | MRGPRX1 (0.40) | SMN1; SMN2RAB9ATSHRNPC1MAPT | |
| SCHEMBL31158808 | 0.64 | SMN1; SMN2 (0.40) | SMN1; SMN2RAB9ATSHRNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |