SCHEMBL8915913

SCHEMBL8915913

Cc1cc(C)c(C[PH](=O)OC(O)Cc2ccccc2)c(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LAP3 P28838 1/20 0.38
TACR1 P25103 2/20 0.36
PPARG P37231 6/20 0.36
PPARA Q07869 6/20 0.36
ANPEP P15144 1/20 0.36
ERAP2 Q6P179 1/20 0.36
ERAP1 Q9NZ08 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
PTPN7 P35236 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8637836 0.76 L3MBTL1 (0.40) L3MBTL1KDM4EMEN1POLBMAPT
SCHEMBL28266499 0.73 NR3C1 (0.35) L3MBTL1MEN1POLBKMT2ASLC6A2
SCHEMBL19041260 0.68 SLC6A2 (0.49) TACR1L3MBTL1KDM4EMEN1POLB
SCHEMBL27512724 0.66 FFAR4 (0.36) L3MBTL1MEN1KMT2ASLC6A2SLC6A4
SCHEMBL10885191 0.66 TSHR (0.41) CYP2C9CYP2C19KMT2A
SCHEMBL4138678 0.66 CYP1A2 (0.39) LAP3PPARGPPARAANPEP
SCHEMBL2722493 0.65 L3MBTL1 (0.49) L3MBTL1MEN1MAPTKMT2AHSD17B10
SCHEMBL3109009 0.65 TACR1 (0.39) TACR1PPARGPPARAANPEPERAP2
SCHEMBL24700133 0.64 SLC6A2 (0.31) MEN1MAPTKMT2ASLC6A2SLC6A4
SCHEMBL3019968 0.64 NOS3 (0.53) L3MBTL1KDM4EMEN1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5679863-A Preparation of carbonylphosphine oxides BASF AKTIENGESELLSCHAFT (DE) 1997-10-21 US disclosed
US-5504236-A Preparation of α-carbonylphosphine oxides BASF AKTIENGESELLSCHAFT (DE) 1996-04-02 US disclosed