SCHEMBL8637836

SCHEMBL8637836

Cc1cc(C)c(C[PH](=O)OCCc2ccccc2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.40
GAA P10253 1/20 0.37
NR3C1 P04150 1/20 0.37
HTR1A P08908 1/20 0.36
HTR2A P28223 1/20 0.36
HTR7 P34969 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR6 P50406 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
RAB9A P51151 3/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
NPC1 O15118 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ATM Q13315 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28983948 0.79 L3MBTL1 (0.42) L3MBTL1GAANR3C1HTR1AHTR2A
SCHEMBL28266499 0.76 NR3C1 (0.35) L3MBTL1NR3C1MEN1KMT2ARAB9A
SCHEMBL8915913 0.76 LAP3 (0.38) L3MBTL1NR3C1MEN1KMT2ACYP2C9
SCHEMBL225077 0.74 GAA (0.41) L3MBTL1GAAMEN1KMT2ARAB9A
SCHEMBL19974320 0.74 CA1 (0.43) HTR1AHTR2AADRA1ARAB9ACA1
SCHEMBL6417967 0.73 L3MBTL1 (0.33) L3MBTL1GAANR3C1HTR1AHTR2A
SCHEMBL6030733 0.72 CA1 (0.44) L3MBTL1HTR2ARAB9ACYP3A4CA1
SCHEMBL2722493 0.71 L3MBTL1 (0.49) L3MBTL1GAANR3C1MEN1KMT2A
SCHEMBL3019968 0.70 NOS3 (0.53) L3MBTL1HTR2AMEN1KMT2ARAB9A
SCHEMBL1101315 0.69 CA1 (0.48) HTR2ARAB9ACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0588159-B1 Process for preparing alpha-carbonyl-phospine oxides BASF AG (DE) 1998-07-29 EP claimed