Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AOC1 | P19801 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604157 | 1.00 | DPYD (0.53) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL8916616 | 0.82 | DPYD (0.46) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL7599202 | 0.82 | DPYD (0.46) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL7602259 | 0.79 | DPYD (0.50) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL7602267 | 0.79 | DPYD (0.50) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL7607771 | 0.77 | DPYD (0.49) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL8776005 | 0.75 | DPYD (0.59) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL65892 | 0.75 | DPYD (0.62) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL933037 | 0.75 | DPYD (0.59) | DPYDGAAMAPTALDH1A1LMNA | |
| SCHEMBL190003 | 0.75 | DPYD (0.62) | DPYDGAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594987-B1 | NUCLEIC ACID SEQUENCING METHODS, KITS AND REAGENTS | GENEFORM TECHNOLOGIES LTD (GB) | 2009-05-27 | — | — | EP | disclosed |
| US-5668266-A | Synthesis of single-stranded labelled oligonucleotides of preselected sequence | SYNGENE, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| US-5541313-A | Single-stranded labelled oligonucleotides of preselected sequence | MOLECULAR BIOSYSTEMS, INC. (US) | 1996-07-30 | — | — | US | disclosed |