Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HBB | P68871 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512588 | 1.00 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL15798473 | 0.83 | DPYD (0.62) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL65892 | 0.83 | DPYD (0.62) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190003 | 0.83 | DPYD (0.62) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190328 | 0.80 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190329 | 0.80 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190378 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL190377 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL8966741 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA | |
| SCHEMBL8776005 | 0.79 | DPYD (0.59) | DPYDMAPTALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245479-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2011-10-06 | — | — | US | claimed |
| EP-2069529-A2 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | Somalogic, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2009012418-A2 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC, INC. (US) | 2009-01-22 | — | — | WO | claimed |
| US-20090004667-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC, INC. (US) | 2009-01-01 | — | — | US | claimed |
| EP-1994171-A2 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SomaLogic, Inc. (US) | 2008-11-26 | — | — | EP | claimed |
| EP-0736105-B1 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS | SOMALOGIC INC (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2007084886-A2 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SOMALOGIC, INCORPORATED (US) | 2007-07-26 | — | — | WO | claimed |
| US-20070166740-A1 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SOMALOGIC, INCORPORATED (US) | 2007-07-19 | — | — | US | claimed |
| US-20070166741-A1 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SOMALOGIC, INCORPORATED (US) | 2007-07-19 | — | — | US | claimed |
| US-20040132067-A1 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SOMALOGIC, INC. | 2004-07-08 | — | — | US | claimed |
| US-20030054360-A1 | Method and apparatus for the automated generation of nucleic acid ligands | SOMALOGIC, INC. | 2003-03-20 | — | — | US | claimed |
| US-6482594-B2 | Made by exposing nucleic acid candidate sequences having photoreactive groups to the target molecule, irradiating complexes formed to crosslink, and separating the crosslinked complexes and amplifying to give the ligands | SOMALOGIC, INC. | 2002-11-19 | — | — | US | claimed |
| WO-2002077262-A2 | METHOD AND APPARATUS FOR THE AUTOMATED GENERATION OF NUCLEIC ACID LIGANDS | SOMALOGIC, INC. (US) | 2002-10-03 | — | — | WO | claimed |
| US-20020106652-A1 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SOMALOGIC, INC. | 2002-08-08 | — | — | US | claimed |
| US-6001577-A | SCREENING FOR LIGANDS ASSOCIATED WITH A DISEASE BY DETECTING LIGAND THAT PHOTOCROSSLINKS TO TARGET WITH PHOTOREACTIVE GROUPS FROM CANDIDATE MIXTURE, REMOVING ANY NUCLEIC ACIDS WITH AFFINITIES NOT ASSOCIATED WITH DISEASE, AND AMPLIFYING | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-12-14 | — | — | US | claimed |
| EP-0736105-A4 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS AND SOLUTION SELEX | UNIV RESEARCH CORP (US) | 1998-10-28 | — | — | EP | claimed |
| US-5763177-A | SELEX IS AN ACRONYM FOR SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT; USEFUL FOR DIAGNOSIS AND/OR TREATMENT OF DISEASES OR PATHOLOGICAL OR TOXIC STATES | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-06-09 | — | — | US | claimed |
| EP-0736105-A1 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS AND SOLUTION SELEX | NeXstar Pharmaceuticals, Inc. (US) | 1996-10-09 | — | — | EP | claimed |
| WO-1995008003-A1 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS AND SOLUTION SELEX | UNIVERSITY RESEARCH CORPORATION (US) | 1995-03-23 | — | — | WO | claimed |
| EP-4056711-B1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC OPERATING CO INC (US) | 2025-09-03 | — | — | EP | disclosed |
| US-12098370-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC OPERATING CO., INC. (US) | 2024-09-24 | — | — | US | disclosed |
| CN-118064441-A | Methods of producing aptamers with improved dissociation rates | 私募蛋白质体运营有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3284832-B1 | APTAMER WITH IMPROVED RATE OF DISSOCIATION, AND NON-COVALENT APTAMER-TARGET COMPLEX THEREOF | SOMALOGIC OPERATING CO INC (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-4056711-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SomaLogic Operating Co., Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| EP-2172566-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC INC (US) | 2022-05-18 | — | — | EP | disclosed |
| US-20220090080-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2022-03-24 | — | — | US | disclosed |
| US-11111495-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-10648972-B2 | Multiplexed analyses of test samples | SOMALOGIC, INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190330634-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC OPERATING CO., INC. | 2019-10-31 | — | — | US | disclosed |
| US-10422794-B2 | Multiplexed analyses of test samples | SOMALOGIC, INC. (US) | 2019-09-24 | — | — | US | disclosed |
| US-20190264208-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. | 2019-08-29 | — | — | US | disclosed |
| US-10316321-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC INC. (US) | 2019-06-11 | — | — | US | disclosed |
| US-20180156787-A1 | Multiplexed Analyses of Test Samples | SOMALOGIC OPERATING CO., INC. | 2018-06-07 | — | — | US | disclosed |
| US-20180155725-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| EP-3284832-A2 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | Somalogic, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| EP-2933340-B1 | Aptamers with uridines and/or thymidines substituted at the 5-position with a benzyl group | SOMALOGIC INC (US) | 2017-09-06 | — | — | EP | disclosed |
| EP-2952894-B1 | Kits comprising aptamers | SOMALOGIC INC (US) | 2017-08-30 | — | — | EP | disclosed |
| US-20170137819-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. | 2017-05-18 | — | — | US | disclosed |
| EP-2451981-B1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC INC (US) | 2016-10-19 | — | — | EP | disclosed |
| EP-2076613-B1 | ANALYSES OF TEST SAMPLES | SOMALOGIC INC (US) | 2016-09-07 | — | — | EP | disclosed |
| US-9404919-B2 | Multiplexed analyses of test samples | SOMALOGIC, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-9382533-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2016-07-05 | — | — | US | disclosed |
| EP-2952894-A1 | KITS COMPRISING APTAMERS | Somalogic, Inc. (US) | 2015-12-09 | — | — | EP | disclosed |
| EP-2933340-A1 | Chemically modified aptamers with improved off-rates | Somalogic, Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| US-20150197753-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. | 2015-07-16 | — | — | US | disclosed |
| US-20150168388-A1 | Multiplexed Analyses of Test Samples | SOMALOGIC OPERATING CO., INC. | 2015-06-18 | — | — | US | disclosed |
| US-20150148237-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC OPERATING CO. INC. | 2015-05-28 | — | — | US | disclosed |
| EP-2613147-B1 | Detection methods using aptamers | SOMALOGIC INC (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-1994171-B1 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SOMALOGIC INC (US) | 2015-03-11 | — | — | EP | disclosed |
| US-8975026-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-8975388-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| EP-2172566-B1 | Method for generating aptamers with improved off-rates | SOMALOGIC INC (US) | 2015-03-04 | — | — | EP | disclosed |
| US-8945830-B2 | Multiplexed analyses of test samples | SOMALOGIC, INC. (US) | 2015-02-03 | — | — | US | disclosed |
| EP-2489743-B1 | Aptamers with 5-(N-naphthyl)-substituted uridines | SOMALOGIC INC (US) | 2015-01-07 | — | — | EP | disclosed |
| US-20140249043-A1 | Multiplexed Analyses of Test Samples | SOMALOGIC, INC. (US) | 2014-09-04 | — | — | US | disclosed |
| WO-2014128289-A1 | BIOMEDICAL DEVICE IMPLANTABLE IN BONE AND/OR CARTILAGINOUS TISSUE, AND CORRESPONDING METHOD TO MANUFACTURE SAID BIOMEDICAL DEVICE | LUMETTI, SIMONE (IT) | 2014-08-28 | — | — | WO | disclosed |
| EP-2626436-A2 | Method for detecting a target using chemically modified aptamers enriched for slow off-rates | Somalogic, Inc. (US) | 2013-08-14 | — | — | EP | disclosed |
| EP-2613147-A1 | Detection methods using aptamers | Somalogic, Inc. (US) | 2013-07-10 | — | — | EP | disclosed |
| US-8409795-B2 | Selex and photoSELEX | SOMALOGIC, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-8404830-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| EP-2069529-B1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC INC (US) | 2013-01-09 | — | — | EP | disclosed |
| EP-2489743-A2 | Chemically modified aptamers with improved off-rates | Somalogic, Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| EP-2451981-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | Somalogic, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| US-20120115752-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2012-05-10 | — | — | US | disclosed |
| US-8071288-B2 | Solid phase synthesis; photocrosslinking; binds specifically to HIV gp120; biochips | SOMALOGIC, INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-20110245479-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2011-10-06 | — | — | US | disclosed |
| EP-2336314-A1 | Improved selex and photoselex | Somalogic, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| US-7964356-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20110136099-A1 | Multiplexed Analyses of Test Samples | SOMALOGIC, INC. (US) | 2011-06-09 | — | — | US | disclosed |
| US-7947447-B2 | Method for generating aptamers with improved off-rates | SOMALOGIC, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-20110082286-A1 | Method for Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2011-04-07 | — | — | US | disclosed |
| WO-2011006075-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC, INC. (US) | 2011-01-13 | — | — | WO | disclosed |
| US-7855054-B2 | Multiplexed analyses of test samples | SOMALOGIC, INC. (US) | 2010-12-21 | — | — | US | disclosed |
| US-20100317120-A1 | test sample is contacted with an aptamer that includes a tag and has a specific affinity for a target molecule; provide high sensitivity assays by optimizing conditions that affect the activity of aptamers and the efficiency of achieving binding equilibria for aptamer-target molecule complexes | SOMALOGIC, INC. (US) | 2010-12-16 | — | — | US | disclosed |
| EP-2172566-A1 | Method for generating aptameters with improved off-rates | Somalogic, Inc. (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20100055695-A1 | Method For Generating Aptamers with Improved Off-Rates | SOMALOGIC, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2069496-A1 | IMPROVED SELEX AND PHOTOSELEX | Somalogic, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-2069529-A2 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | Somalogic, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20090098549-A1 | SELEX AND PHOTOSELEX | SOMALOGIC, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| US-20090042206-A1 | Multiplexed Analyses of Test Samples | SOMALOGIC, INC. (US) | 2009-02-12 | — | — | US | disclosed |
| WO-2009012410-A1 | IMPROVED SELEX AND PHOTOSELEX | SOMALOGIC, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009012418-A2 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| US-20090004667-A1 | METHOD FOR GENERATING APTAMERS WITH IMPROVED OFF-RATES | SOMALOGIC, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| EP-1994171-A2 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SomaLogic, Inc. (US) | 2008-11-26 | — | — | EP | disclosed |
| US-20080160535-A1 | Methods and Reagents for Detecting Target Binding by Nucleic Acid Ligands | SOMALOGIC, INC. (US) | 2008-07-03 | — | — | US | disclosed |
| EP-1889910-A2 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SomaLogic, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| EP-0736105-B1 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS | SOMALOGIC INC (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2007084886-A2 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SOMALOGIC, INCORPORATED (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070166740-A1 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SOMALOGIC, INCORPORATED (US) | 2007-07-19 | — | — | US | disclosed |
| US-20070166741-A1 | MULTIPLEXED ANALYSES OF TEST SAMPLES | SOMALOGIC, INCORPORATED (US) | 2007-07-19 | — | — | US | disclosed |
| US-20060057573-A1 | Methods and reagents for detecting target binding by nucleic acid ligands | SOMALOGIC, INC (US) | 2006-03-16 | — | — | US | disclosed |
| EP-1194174-B1 | EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD | UNIV ALBERTA SIMON FRASER UNI (CA) | 2005-09-21 | — | — | EP | disclosed |
| EP-1481090-A1 | METHODS AND REAGENTS FOR DETECTING TARGET BINDING BY NUCLEIC ACID LIGANDS | SomaLogic, Inc. (US) | 2004-12-01 | — | — | EP | disclosed |
| US-6780850-B1 | INHIBITING DEGRADATION OF A NUCLEIC ACID IN THE BLOOD COMPRISING ATTACHING STREPTAVIDIN OR A VARIANT THEREOF THAT RETAINS BIOTIN BINDING ACTIVITY TO SAID NUCLEIC ACID | TRIUMF (CA) | 2004-08-24 | — | — | US | disclosed |
| US-20040132067-A1 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SOMALOGIC, INC. | 2004-07-08 | — | — | US | disclosed |
| WO-2003070984-A1 | METHODS AND REAGENTS FOR DETECTING TARGET BINDING BY NUCLEIC ACID LIGANDS | SOMALOGIC, INC. (US) | 2003-08-28 | — | — | WO | disclosed |
| US-6610841-B1 | Nucleic acid ligand covalently bonded via a hydrolyzable junctional ester bond to a drug component; sustained-release; effective drug delivery system with reduced toxicity | GILEAD SCIENCES, INC. | 2003-08-26 | — | — | US | disclosed |
| US-20030054360-A1 | Method and apparatus for the automated generation of nucleic acid ligands | SOMALOGIC, INC. | 2003-03-20 | — | — | US | disclosed |
| WO-2003014369-A1 | NUCLEIC ACID LIGANDS WITH INTRAMOLECULAR DUPLEXES | SOMALOGIC, INC. (US) | 2003-02-20 | — | — | WO | disclosed |
| WO-2002077262-A2 | METHOD AND APPARATUS FOR THE AUTOMATED GENERATION OF NUCLEIC ACID LIGANDS | SOMALOGIC, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| US-20020106652-A1 | Systematic evolution of ligands by exponential enrichment: photoselection of nucleic acid ligands and solution selex | SOMALOGIC, INC. | 2002-08-08 | — | — | US | disclosed |
| EP-1194174-A2 | EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD | The University Of Alberta, Simon Fraser Uni., The Uni. of Victoria, And The Uni. Of British Columbia doing business as TRIUMF (CA) | 2002-04-10 | — | — | EP | disclosed |
| EP-0649840-B1 | Bis(hydroxymethyl)cyclopropylmethyl pyrimidine derivatives, their preparation and their use as anti-viral agents | AJINOMOTO KK (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6291184-B1 | DETECTING TARGET MOLECULES IN A BIOLOGICAL SUBSTANCE ASSOCIATED WITH DISEASES BY EXPOSING SUBSTANCE TO A NUCLEIC ACID LIGAND THAT PHOTOCROSSLINKS TO A TARGET MOLECULE; IRRADIATING THE SUBSTANCE CONTAINING LIGAND, DETECT COMPLEXES | SOMALOGIC, INC. | 2001-09-18 | — | — | US | disclosed |
| WO-2000078364-A2 | EXTENDING THE LIFETIME OF ANTICOAGULANT OLIGODEOXYNUCLEOTIDE APTAMERS IN BLOOD | THE UNIVERSITY OF ALBERTA; SIMON FRASER UNIVERSITY; THE UNIVERSITY OF VICTORIA; THE UNIVERSITY OF BRITISH COLUMBIA DOING BUSINESS AS TRIUMF (CA) | 2000-12-28 | — | — | WO | disclosed |
| US-6001577-A | SCREENING FOR LIGANDS ASSOCIATED WITH A DISEASE BY DETECTING LIGAND THAT PHOTOCROSSLINKS TO TARGET WITH PHOTOREACTIVE GROUPS FROM CANDIDATE MIXTURE, REMOVING ANY NUCLEIC ACIDS WITH AFFINITIES NOT ASSOCIATED WITH DISEASE, AND AMPLIFYING | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1999030561-A1 | NUCLEOTIDE-BASED PRODRUGS | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0736105-A4 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS AND SOLUTION SELEX | UNIV RESEARCH CORP (US) | 1998-10-28 | — | — | EP | disclosed |
| US-5763177-A | SELEX IS AN ACRONYM FOR SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT; USEFUL FOR DIAGNOSIS AND/OR TREATMENT OF DISEASES OR PATHOLOGICAL OR TOXIC STATES | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| EP-0736105-A1 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS AND SOLUTION SELEX | NeXstar Pharmaceuticals, Inc. (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5496824-A | ZOSTER VIRUS WITH PYRIMIDINEDIONE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0649840-A1 | Bis(hydroxymethyl)cyclopropylmethyl pyrimidine derivatives, their preparation and their use as anti-viral agents | Ajinomoto Co., Inc. (JP) | 1995-04-26 | — | — | EP | disclosed |
| WO-1995008003-A1 | SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS AND SOLUTION SELEX | UNIVERSITY RESEARCH CORPORATION (US) | 1995-03-23 | — | — | WO | disclosed |
| US-4668778-A | Nucleoside 5'-alkyl- or alkenylphosphate | YAMASA SHOYU KABUSHIKI KAISHA (JP) | 1987-05-26 | — | — | US | disclosed |
| EP-0097376-B1 | NUCLEOSIDE 5'-ALKYL- OR ALKENYLPHOSPHATE | Yamasa Shoyu Kabushiki Kaisha (JP) | 1986-09-17 | — | — | EP | disclosed |
| EP-0097376-A1 | Nucleoside 5'-alkyl- or alkenylphosphate | Yamasa Shoyu Kabushiki Kaisha (JP) | 1984-01-04 | — | — | EP | disclosed |
| US-4424211-A | VIRICIDES | REGA INSTITUUT VZW (BE) | 1984-01-03 | — | — | US | disclosed |
| US-4424211-A | VIRICIDES | REGA INSTITUUT VZW (BE) | 1984-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082286-A1 | Method for Generating Aptamers with Improved Off-Rates | DDX1, DDX3X, DDX18 | DPYD 295/4885MAPT 3254/4885ALDH1A1 3530/4885 |
| US-20110245479-A1 | Method for Generating Aptamers with Improved Off-Rates | DDX1, DDX3X, DDX18 | DPYD 295/4885MAPT 3254/4885ALDH1A1 3530/4885 |
| US-20120115752-A1 | Method for Generating Aptamers with Improved Off-Rates | CD2BP2, ENTPD8, ENTPD1 | DPYD 497/4885MAPT 1852/4885ALDH1A1 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.