SCHEMBL190003

SCHEMBL190003

O=c1[nH]cc(/C=C/Br)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DPYD Q12882 5/20 0.62
MAPT P10636 4/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 2/20 0.43
ATAD2 Q6PL18 1/20 0.43
LMNA P02545 1/20 0.43
CYP19A1 P11511 1/20 0.43
TSHR P16473 1/20 0.43
THPO P40225 1/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.43
HBB P68871 1/20 0.43
PMP22 Q01453 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4C Q9H3R0 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL65892 1.00 DPYD (0.62) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL14793573 0.91 DPYD (0.66) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL6512588 0.83 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL933037 0.83 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL5559312 0.82 ATAD2 (0.53) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL5559308 0.82 ATAD2 (0.53) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL8966741 0.79 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL8776005 0.79 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL12903446 0.79 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2
SCHEMBL190328 0.76 DPYD (0.59) DPYDMAPTALDH1A1GAAATAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 976 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
US-10260071-B2 CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity COLEY PHARMACEUTICAL GMBH (DE) 2019-04-16 US claimed
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 US claimed
US-9677067-B2 Compositions and methods for synthetic gene assembly Twist Bioscience Corporation (US) 2017-06-13 US claimed
US-20170159044-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2017-06-08 US claimed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 US claimed
EP-3157573-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
EP-3157572-A2 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Moderna Therapeutics, Inc. (US) 2017-04-26 EP claimed
US-20160348115-A1 CpG Oligonucleotide Analogs Containing Hydrophobic T Analogs with Enhanced Immunostimulatory Activity PFIZER INC. 2016-12-01 US claimed
CN-106170553-A Modified nucleic acid molecules and uses thereof 现代治疗公司 2016-11-30 CN claimed
EP-0475992-A1 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1992-03-25 EP claimed
EP-0464511-A2 Process for the preparation of acyclic, substituted nucleosides and its intermediates HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-08 EP claimed
EP-0283065-B1 COMBINATIONS OF FU AND BVU AS ANTI-ADENOCARCINOMA AGENTS Stichting REGA V.Z.W. (BE) 1991-05-29 EP claimed
US-4988678-A Fluorouracil and tetrahydrofuryl-5-fluorouracil as an antitumor agent and bromovinyluracil and 5-(2-bromovinyl-2'-deoxyuridine STICHTING REGA VZW (BE) 1991-01-29 US claimed
WO-1990015064-A1 THERAPEUTIC NUCLEOSIDES THE WELLCOME FOUNDATION LIMITED (GB) 1990-12-13 WO claimed
EP-0391411-A2 3'-Substituted methyl nucleosides as antiviral agents Bristol-Myers Squibb Company (US) 1990-10-10 EP claimed
US-4894365-A 5-FLUOROURACIL AND BROMOVINYLURACIL STICHTING REGA VZW (BE) 1990-01-16 US claimed
EP-0283065-A1 Combinations of FU and BVU as anti-adenocarcinoma agents Stichting REGA V.Z.W. (BE) 1988-09-21 EP claimed
EP-0273169-A2 Novel antiviral agents SRI INTERNATIONAL (US) 1988-07-06 EP claimed
WO-1984004748-A2 NOVEL ANTIVIRAL AGENTS 1984-12-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 DPYD 369/4885MAPT 3589/4885ALDH1A1 2324/4885
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 DPYD 369/4885MAPT 3589/4885ALDH1A1 2324/4885
US-10260071-B2 CpG oligonucleotide analogs containing hydrophobic T analogs with enhanced immunostimulatory activity TLR9, TYMP, STING1 DPYD 34/4885MAPT 4234/4885ALDH1A1 4515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.