Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.36 |
| ▸ | DRD2 | P14416 | 8/20 | 0.36 |
| ▸ | HTR7 | P34969 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915767 | 0.89 | HTR2A (0.38) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| SCHEMBL8918426 | 0.86 | HTR2A (0.44) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| SCHEMBL8917651 | 0.86 | HTR2A (0.40) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| SCHEMBL8917038 | 0.85 | HTR2A (0.50) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| Oxalic Acid SCHEMBL8916497 | 0.84 | DRD2 (0.45) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL8918089 | 0.84 | DRD2 (0.54) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| SCHEMBL8917017 | 0.83 | HTR2A (0.46) | HTR2ADRD2KCNH2SLC6A4HTR1A | |
| SCHEMBL8917987 | 0.82 | HTR2A (0.49) | HTR2ADRD2HTR7KCNH2SLC6A4 | |
| SCHEMBL8920275 | 0.81 | DRD2 (0.47) | HTR2ADRD2HTR7KCNH2HTR1A | |
| SCHEMBL8920271 | 0.79 | DRD2 (0.56) | HTR2ADRD2HTR7KCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |