Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639936 | 0.94 | ALDH1A1 (0.47) | POLBHTTALDH1A1MAPTTP53 | |
| SCHEMBL6518281 | 0.92 | HTT (0.47) | POLBHTTALDH1A1MAPTCYP3A4 | |
| SCHEMBL8840306 | 0.89 | HTT (0.44) | POLBHTTALDH1A1MAPTTP53 | |
| SCHEMBL9447365 | 0.86 | HTT (0.42) | POLBHTTALDH1A1MAPTCYP3A4 | |
| SCHEMBL11035064 | 0.84 | KIF11 (0.47) | POLBHTTALDH1A1MAPTCYP3A4 | |
| SCHEMBL2891481 | 0.82 | POLB (0.67) | POLBHTTALDH1A1TP53CYP3A4 | |
| SCHEMBL9683683 | 0.82 | POLB (0.61) | POLBHTTALDH1A1MAPTTP53 | |
| SCHEMBL11049728 | 0.81 | NR3C2 (0.44) | POLBHTTALDH1A1MAPTCYP3A4 | |
| SCHEMBL9684130 | 0.79 | POLB (0.50) | POLBHTTALDH1A1MAPTNOS3 | |
| SCHEMBL13497781 | 0.78 | HTT (0.45) | POLBHTTALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608013-A | Polyimides and thermosetting resin compositions containing the same | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0456515-A1 | Polyimides and thermosetting resin compositions containing the same | Hitachi Chemical Co., Ltd. (JP) | 1991-11-13 | — | — | EP | disclosed |