Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684130 | 0.89 | POLB (0.50) | POLBALDH1A1HTTMAPTHTR1D | |
| SCHEMBL7639936 | 0.88 | ALDH1A1 (0.47) | POLBALDH1A1HTTMAPTHTR1D | |
| SCHEMBL13497781 | 0.84 | HTT (0.45) | POLBALDH1A1HTTMAPTHTR1D | |
| SCHEMBL8840306 | 0.82 | HTT (0.44) | POLBALDH1A1HTTMAPTNOS3 | |
| SCHEMBL23557907 | 0.82 | ALDH1A1 (0.46) | POLBALDH1A1HTTMAPTNOS3 | |
| SCHEMBL8916205 | 0.82 | POLB (0.48) | POLBALDH1A1HTTMAPTHTR1D | |
| SCHEMBL9863958 | 0.81 | POLB (0.41) | POLBALDH1A1HTTMAPTHTR1D | |
| SCHEMBL13791752 | 0.80 | POLB (0.42) | POLBALDH1A1HTTMAPTHTR1D | |
| SCHEMBL22050362 | 0.80 | KIF11 (0.48) | POLBALDH1A1HTTMAPTNOS3 | |
| SCHEMBL2231480 | 0.79 | POLB (0.94) | POLBALDH1A1MAPTHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0492473-A1 | Process for the preparation of 4-substituted 2,6-dialkylanilines | LONZA AG (CH) | 1992-07-01 | — | — | EP | disclosed |