Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8917071 | 0.99 | KDM4E (0.42) | KDM4EGAAHTR6TP53SMN1; SMN2 | |
| SCHEMBL8916564 | 0.93 | KDM4E (0.41) | KDM4EGAAHTR6TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8917131 | 0.92 | KDM4E (0.41) | KDM4EGAAHTR6TP53SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8916094 | 0.83 | DRD2 (0.42) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8916858 | 0.76 | HSD11B1 (0.49) | GAASMN1; SMN2DRD2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8917654 | 0.73 | HSD11B1 (0.46) | KDM4EGAASMN1; SMN2DRD2HTR2A | |
| SCHEMBL8306212 | 0.73 | HTR2A (0.55) | SMN1; SMN2DRD2HTR2A | |
| Hydrochloric Acid SCHEMBL9073679 | 0.72 | HTR2A (0.54) | SMN1; SMN2DRD2HTR2A | |
| SCHEMBL8306860 | 0.72 | HTR1A (0.62) | DRD2 | |
| SCHEMBL8916231 | 0.70 | DRD2 (0.41) | KDM4ETP53SMN1; SMN2DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703070-A | PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |