Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392516 | 0.85 | PTGS2 (0.54) | PTGS2AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL8396683 | 0.82 | AKR1C3 (0.51) | PTGS2AKR1C3PTGS1 | |
| SCHEMBL401165 | 0.81 | CES2 (0.46) | — | |
| SCHEMBL265232 | 0.79 | PTGS2 (0.69) | PTGS2MAOBAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL7814053 | 0.78 | MAOB (0.63) | PTGS2MAOBAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL23341534 | 0.76 | CES2 (0.55) | PTGS2MAOBMGLL | |
| SCHEMBL6881812 | 0.74 | PTGS2 (0.47) | PTGS2MAOBAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL11327650 | 0.74 | CES2 (0.54) | PTGS2MAOB | |
| SCHEMBL5052857 | 0.73 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8100571 | 0.70 | PTGS2 (0.46) | PTGS2MAOBAKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686460-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | LABORATOIRES UPSA (FR) | 1997-11-11 | — | — | US | disclosed |