SCHEMBL8916285

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16255724	0.88	TSHR (0.56)	ALOX15TSHRHSD17B10NPC1RAB9A
	SCHEMBL17888270	0.78	AKR1C3 (0.50)	TSHRLMNAGAAALDH1A1TP53
	SCHEMBL12286004	0.77	GAA (0.50)	NPC1KDM4ELMNASMN1; SMN2POLB
	SCHEMBL8916950	0.76	ALDH1A1 (0.59)	NPC1RAB9AKDM4ELMNASMN1; SMN2
	SCHEMBL7882466	0.76	KDM4E (0.39)	HSD17B10KDM4ELMNASMN1; SMN2POLB
	SCHEMBL7918576	0.75	NAMPT (0.54)	ALOX15TSHRKDM4ESMN1; SMN2ALDH1A1
	SCHEMBL26981196	0.73	HSD17B10 (0.91)	ALOX15TSHRHSD17B10NPC1RAB9A
	SCHEMBL21423709	0.72	KDM4E (0.42)	ALOX15KDM4ELMNASMN1; SMN2POLB
	SCHEMBL11959926	0.72	CCNT1 (0.39)	TSHRHSD17B10KDM4ELMNASMN1; SMN2
	SCHEMBL4472888	0.72	TSHR (0.58)	ALOX15TSHRHSD17B10NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.