Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916301 | 1.00 | ALDH1A1 (0.55) | ALDH1A1MAPTKDM4EHPGDTRPA1 | |
| SCHEMBL8845678 | 0.93 | MAPT (0.55) | ALDH1A1MAPTKDM4EHPGDTRPA1 | |
| SCHEMBL8845672 | 0.93 | MAPT (0.55) | ALDH1A1MAPTKDM4EHPGDTRPA1 | |
| SCHEMBL13579994 | 0.91 | KDM4E (0.66) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL7335620 | 0.85 | KDM4E (0.53) | ALDH1A1MAPTKDM4EHPGDTRPA1 | |
| SCHEMBL4465918 | 0.83 | MAPT (0.56) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL4465915 | 0.83 | MAPT (0.56) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL8614831 | 0.81 | ALDH1A1 (0.81) | ALDH1A1MAPTKDM4EHPGDTRPA1 | |
| SCHEMBL9858496 | 0.81 | MAPT (0.58) | ALDH1A1MAPTKDM4EHPGDTRPA1 | |
| SCHEMBL6065194 | 0.80 | PLAU (0.50) | ALDH1A1MAPTKDM4EHPGDTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663207-A | ADMINISTERING TO INHIBIT DEVELOPMENT OF BREAST TUMOR | RESEARCH CORPORATION TECHNOLOGIES (US) | 1997-09-02 | — | — | US | disclosed |
| US-5397802-A | Gem-dichlorocyclopropanes as antitumor agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-14 | — | — | US | disclosed |