Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | GPR183 | P32249 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465915 | 1.00 | MAPT (0.56) | MAPTALDH1A1KDM4EHPGDMAOA | |
| SCHEMBL13579994 | 0.91 | KDM4E (0.66) | MAPTALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL8916301 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL8845678 | 0.83 | MAPT (0.55) | MAPTALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL8916304 | 0.83 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL8845672 | 0.83 | MAPT (0.55) | MAPTALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL9789510 | 0.81 | NQO2 (0.65) | MAPTALDH1A1KDM4EHPGDMAOA | |
| SCHEMBL9789497 | 0.81 | MAPT (0.58) | MAPTALDH1A1KDM4EHPGDMAOA | |
| SCHEMBL9789495 | 0.81 | MAPT (0.58) | MAPTALDH1A1KDM4EHPGDMAOA | |
| SCHEMBL9789516 | 0.81 | NQO2 (0.65) | MAPTALDH1A1KDM4EHPGDMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7479575-B2 | Method for preparing para-phenyl alkynyl benzaldehydes | LABORATOIRES SERONO SA (CH) | 2009-01-20 | — | — | US | disclosed |
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2008-05-08 | — | — | US | disclosed |
| EP-1675813-B1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | SERONO LAB (CH) | 2007-12-19 | — | — | EP | disclosed |
| EP-1675813-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | Applied Research Systems ARS Holding N.V. (NL) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037758-A1 | METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108849-A1 | Method For Preparing Para-Phenyl Alkynyl Benzaldehydes | TNNC1, CPT1B, MUSK | MAPT 4533/4885ALDH1A1 200/4885KDM4E 2673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.