Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8917790 | 0.97 | PDE10A (0.39) | PDE10AELANE | |
| Hydrochloric Acid SCHEMBL8917342 | 0.82 | HTR2A (0.36) | PDE10A | |
| Hydrochloric Acid SCHEMBL5352654 | 0.77 | HTR2A (0.47) | PDE10A | |
| Hydrochloric Acid SCHEMBL8917252 | 0.76 | HTR2A (0.42) | PDE10A | |
| Hydrochloric Acid SCHEMBL6559419 | 0.76 | MAPT (0.35) | PDE10A | |
| Hydrochloric Acid SCHEMBL6557592 | 0.73 | HTR2A (0.36) | PDE10A | |
| Hydrochloric Acid SCHEMBL8916641 | 0.73 | MEN1 (0.34) | — | |
| SCHEMBL27335604 | 0.71 | HTR2A (0.44) | PDE10A | |
| SCHEMBL28398746 | 0.70 | ELANE (0.42) | ELANE | |
| Hydrochloric Acid SCHEMBL7251524 | 0.69 | MYC (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5668230-A | METALLOCENE WITH ETHYLENE BRIDGED FLUORENE UNITS, ALUMOXANE COCATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-09-16 | — | — | US | claimed |