Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037829 | 0.87 | NOS2 (0.42) | TLR8KDM4EMAPTHPGDSMN1; SMN2 | |
| SCHEMBL22791948 | 0.81 | LIPG (0.40) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL9189865 | 0.80 | NOS2 (0.39) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL28052894 | 0.79 | TYR (0.44) | KDM4EUSP2ALDH1A1GAAMAPT | |
| SCHEMBL19310672 | 0.79 | TDP1 (0.35) | TLR8MAPTMEN1RAB9AKMT2A | |
| SCHEMBL16828251 | 0.79 | TYR (0.38) | TLR8MAPTMEN1RAB9AKMT2A | |
| SCHEMBL10456083 | 0.79 | TYR (0.44) | KDM4EUSP2ALDH1A1GAAMAPT | |
| SCHEMBL27479136 | 0.79 | TLR8 (0.40) | TLR8KDM4EUSP2ALDH1A1GAA | |
| SCHEMBL21776131 | 0.78 | TLR7 (0.42) | TLR8KDM4EUSP2ALDH1A1GAA | |
| SCHEMBL27900729 | 0.77 | TLR8 (0.47) | TLR8NOS2TLR7HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5686618-A | Method for preparing 3-amino-2-chloro-4-alkylpyridine or-4-arylpyridine | BOEHRINGER INGELHEIM KG (DE) | 1997-11-11 | — | — | US | disclosed |