Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DGKA | P23743 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8916163 | 0.86 | TP53 (0.45) | TP53MAPTALDH1A1LMNACYP2D6 | |
| SCHEMBL8915727 | 0.74 | HTR2C (0.52) | CYP2D6CYP3A4HTR2AHTR2CHTR7 | |
| SCHEMBL8915757 | 0.74 | CTSS (0.51) | TP53MAPTLMNACYP2D6TSHR | |
| SCHEMBL8917702 | 0.73 | TP53 (0.39) | TP53MAPTLMNACYP2D6TSHR | |
| SCHEMBL8916620 | 0.73 | GAA (0.40) | TP53MAPTLMNACYP2D6TSHR | |
| SCHEMBL8917936 | 0.73 | HTR2A (0.53) | ALDH1A1CYP2D6TSHRADRB2HTR1A | |
| SCHEMBL8916147 | 0.73 | DRD2 (0.54) | CYP2D6TSHRADRB2HTR1AADRA2A | |
| SCHEMBL8915764 | 0.73 | BPTF (0.48) | TP53MAPTALDH1A1LMNAHSD17B10 | |
| SCHEMBL8916546 | 0.72 | BPTF (0.47) | TP53MAPTALDH1A1HSD17B10MEN1 | |
| SCHEMBL8916936 | 0.71 | BPTF (0.46) | TP53MAPTALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |