Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 4/20 | 0.45 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | DGKA | P23743 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916882 | 0.86 | TP53 (0.50) | TP53MAPTOPRM1ALDH1A1LMNA | |
| SCHEMBL8915727 | 0.83 | HTR2C (0.52) | CYP2D6HTR2AHTR2CCYP3A4HTR7 | |
| Oxalic Acid SCHEMBL8991806 | 0.78 | CTSS (0.40) | TP53MAPTDRD2HTR2AHTR7 | |
| Oxalic Acid SCHEMBL8916982 | 0.77 | HTR2A (0.42) | TP53MAPTLMNADRD2DRD4 | |
| Oxalic Acid SCHEMBL8919091 | 0.77 | CTSS (0.43) | TP53MAPTGAA | |
| Oxalic Acid SCHEMBL8919160 | 0.77 | TP53 (0.39) | TP53MAPTDRD2HTR2ASLC6A4 | |
| SCHEMBL8916426 | 0.76 | MAPT (0.40) | TP53MAPTLMNAMEN1KMT2A | |
| SCHEMBL8916680 | 0.76 | HTR2C (0.52) | CYP2D6HTR2AHTR2CCYP3A4HTR7 | |
| Oxalic Acid SCHEMBL8917045 | 0.76 | CTSS (0.39) | TP53MAPTDRD2HTR2AHTR7 | |
| SCHEMBL8916994 | 0.75 | HTR2A (0.43) | TP53MAPTMEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |