Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20809490 | 0.82 | HTR2C (0.46) | KCNA3PSMB5 | |
| Hydrochloric Acid SCHEMBL29688593 | 0.81 | HTR2C (0.47) | KCNA3 | |
| Hydrochloric Acid SCHEMBL20135301 | 0.81 | HTR2C (0.47) | KCNA3 | |
| SCHEMBL8917845 | 0.80 | KCNA3 (0.36) | KCNA3 | |
| SCHEMBL8916199 | 0.76 | KMT2A (0.39) | PSMB5POLB | |
| SCHEMBL8920622 | 0.76 | ALDH1A1 (0.39) | PSMB8 | |
| SCHEMBL8917953 | 0.75 | PSMB8 (0.40) | PSMB8 | |
| SCHEMBL8917923 | 0.73 | MAPT (0.39) | POLBPSMB8 | |
| SCHEMBL8920208 | 0.71 | PTPN1 (0.43) | PSMB8 | |
| SCHEMBL5584576 | 0.69 | PSMB5 (0.34) | PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |