Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8917953 | 0.88 | PSMB8 (0.40) | PSMB8CYP17A1ALDH1A1DRD2SLC6A4 | |
| SCHEMBL8917923 | 0.77 | MAPT (0.39) | PSMB8ALDH1A1TSHRDRD2SLC6A4 | |
| SCHEMBL8917162 | 0.77 | PTPN1 (0.40) | PTPN1ALDH1A1DRD2SLC6A4 | |
| SCHEMBL8920622 | 0.77 | ALDH1A1 (0.39) | PSMB8CYP17A1ALDH1A1TSHRDRD2 | |
| SCHEMBL8917899 | 0.71 | CYP11B1 (0.40) | CYP17A1DRD2SLC6A4MCHR1 | |
| SCHEMBL8916901 | 0.71 | KCNA3 (0.36) | PSMB8 | |
| SCHEMBL8916199 | 0.71 | KMT2A (0.39) | ALDH1A1TSHR | |
| SCHEMBL8916173 | 0.71 | PTPN1 (0.40) | PTPN1ALDH1A1DRD2SLC6A4 | |
| SCHEMBL8917187 | 0.71 | MAOB (0.39) | — | |
| SCHEMBL8918420 | 0.71 | PTPN1 (0.40) | PTPN1CYP17A1DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |