Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915727 | 0.84 | HTR2C (0.52) | HTR2AHSD11B1HTR2CHTR7HTR6 | |
| Oxalic Acid SCHEMBL8918084 | 0.81 | MCHR1 (0.39) | GAAMAPTTP53 | |
| Oxalic Acid SCHEMBL8991806 | 0.79 | CTSS (0.40) | HTR2AGAAMAPTTP53HTR7 | |
| SCHEMBL8916680 | 0.78 | HTR2C (0.52) | HTR2AHTR2CHTR7HTR6 | |
| SCHEMBL8916426 | 0.78 | MAPT (0.40) | GAAMAPTTP53HTR1ADRD2 | |
| Oxalic Acid SCHEMBL8919160 | 0.77 | TP53 (0.39) | HTR2AGAAMAPTTP53HTR7 | |
| Oxalic Acid SCHEMBL8919091 | 0.77 | CTSS (0.43) | GAAMAPTTP53 | |
| Oxalic Acid SCHEMBL8916163 | 0.77 | TP53 (0.45) | HTR2AGAAMAPTTP53HTR2C | |
| Oxalic Acid SCHEMBL8917045 | 0.77 | CTSS (0.39) | HTR2AGAAMAPTTP53HTR7 | |
| SCHEMBL8917865 | 0.76 | MAPT (0.38) | HTR2AGAAMAPTTP53HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |