Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8916982 | 0.81 | HTR2A (0.42) | TP53MAPTGAA | |
| SCHEMBL8915727 | 0.79 | HTR2C (0.52) | KDM4E | |
| Hydrochloric Acid SCHEMBL8917029 | 0.76 | MCHR1 (0.41) | MCHR1TP53MAPTKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL8916497 | 0.74 | DRD2 (0.45) | KCNH2 | |
| SCHEMBL8916680 | 0.72 | HTR2C (0.52) | KDM4E | |
| Oxalic Acid SCHEMBL8991806 | 0.72 | CTSS (0.40) | MCHR1TP53MAPTKCNH2GAA | |
| SCHEMBL8917705 | 0.72 | DRD2 (0.52) | MCHR1TP53MAPTKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL8916163 | 0.72 | TP53 (0.45) | TP53MAPTKDM4EALDH1A1KCNH2 | |
| SCHEMBL8916045 | 0.71 | HTR2A (0.36) | MCHR1KCNH2 | |
| Oxalic Acid SCHEMBL8919091 | 0.71 | CTSS (0.43) | MCHR1TP53MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |