Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.52 |
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915727 | 0.93 | HTR2C (0.52) | HTR2CHTR2AHTR7HTR6KDM4E | |
| SCHEMBL8916713 | 0.82 | SLC6A4 (0.39) | HTR2CHTR2AHTR7HTR6CYP3A4 | |
| SCHEMBL8917047 | 0.80 | CTSS (0.42) | HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL8917305 | 0.80 | ACHE (0.36) | HTR2CHTR2AHTR7HTR6CYP2D6 | |
| SCHEMBL8916788 | 0.80 | CTSS (0.42) | HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL8920342 | 0.78 | CTSS (0.49) | HTR2AHTR7 | |
| SCHEMBL8916743 | 0.78 | HTR2A (0.51) | HTR2AHTR7 | |
| SCHEMBL8917101 | 0.78 | DRD2 (0.54) | HTR2AHTR7 | |
| SCHEMBL8916930 | 0.78 | SLC6A4 (0.52) | KDM4ECYP1A2CYP3A4CYP2C19 | |
| Oxalic Acid SCHEMBL8916982 | 0.78 | HTR2A (0.42) | HTR2CHTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |