Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.48 |
| ▸ | TP53 | P04637 | 9/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919052 | 0.88 | MAPT (0.58) | MAPTTP53THRBUSP2LMNA | |
| SCHEMBL8653538 | 0.82 | MAPT (0.48) | MAPTTP53THRBLMNAALDH1A1 | |
| SCHEMBL8915792 | 0.73 | MAPT (0.58) | MAPTTP53THRBUSP2LMNA | |
| SCHEMBL3123741 | 0.72 | MAPT (0.54) | MAPTTP53LMNAPOLBALDH1A1 | |
| SCHEMBL2836561 | 0.72 | MAPT (0.51) | MAPTTP53THRBLMNAPOLB | |
| SCHEMBL22860672 | 0.71 | MAPT (0.79) | MAPTTP53THRBUSP2LMNA | |
| SCHEMBL23010594 | 0.70 | MAPT (0.58) | MAPTTP53THRBUSP2LMNA | |
| SCHEMBL8916906 | 0.70 | DRD2 (0.38) | MAPTTP53THRBUSP2LMNA | |
| SCHEMBL8917934 | 0.70 | MAPT (0.39) | MAPTTP53LMNAPOLBALDH1A1 | |
| SCHEMBL8917269 | 0.70 | ADRB1 (0.34) | MAPTTP53LMNAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | claimed |
| US-5691330-A | ANTIPSYCHOTIC AGENT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-11-25 | — | — | US | disclosed |
| US-5532240-A | ANTIPSYCHOTIC AGENTS AND ANTISEROTONIN AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1996-07-02 | — | — | US | disclosed |